Oxford Covid-19 vaccine reportedly triggers 'correct' immune response

Henrietta Strickland
July 4, 2020

ICMR Director General Balram Bhargava, in a letter to the heads of the selected institutions, informed them that it has partnered with Hyderabad-based Bharat Biotech International Limited (BBIL) to fast-track clinical trials of the indigenous COVID-19 vaccine (BBV152 COVID vaccine).

The company has revealed that human clinical trials will begin across the country this month itself.

Bharat Biotech became the first company to receive clearance from the Drugs Controller General of India (DCGI) to start human trials of its vaccine named Covaxin. Before that, the NIV had isolated the SARS-CoV-2 strain and passed it to the company.

Indonesia's national consortium for COVID-19 vaccine development is aiming to finish its work within the next 18 months in an effort to eradicate the coronavirus in the country.

"Therefore, it is necessary for Indonesia to develop its own COVID-19 vaccine". Besides, it was also reportedly the first firm in the world to find a Zika virus vaccine. The balance capital was funded by way of loan from Technology Development Board (Department of Science and Technology) and IDBI Bank, Dr Ella told Rediff.com. "This is going at a speed no other vaccine has ever gone".

Zydus said, with its ZyCoV-D, it has successfully established the DNA vaccine platform in India using non-replicating and non-integrating plasmid carrying the gene of interest making it very safe.

She also indicated that 8,000 volunteers were already participating in Phase III trial for its vaccine candidate, AZD1222, which has been licensed to AstraZeneca.

It further said no safety concerns were observed for the vaccine candidate in repeat dose toxicology studies by both intramuscular and intradermal routes of administration.

Only the US, Brazil and Russian Federation have reported more cases than India. And these two are not the only ones showing positive early signs. In a statement, the company said, in animal studies the vaccine was found to elicit a strong immune response in multiple animal species like mice, rats, guinea pigs and rabbits.

Other reports by Click Lancashire

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