Studies find almost 300 kids with inflammatory condition tied to Covid-19

Henrietta Strickland
July 1, 2020

Her team's paper reported on 186 children with the condition who were reported by doctors from 26 states.

The U.K. definition of "pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2" (PIMS) released in April was followed by a narrower definition released in May by the CDC and World Health Organization for MIS-C.

Study authors suggest that the higher incidence of MIS-C among black and Hispanic children may be a reflection of the well-documented elevated incidence of COVID-19 infection among black and Hispanic communities. It is considered uncommon and deaths are rare; six children died among the 285 in the new studies.

Including cases in Europe, where it was first reported, about 1,000 children worldwide have been affected, a journal editorial said.

Public health surveillance for multisystem inflammatory syndrome in children (MIS-C) affirmed the distinctive constellation of symptoms, but case definitions may belie a larger burden of less clear disease.

The vast majority of kids got sick over a couple of days mostly with GI symptoms including vomiting and diarrhea that then worsened into belly pain and lack of appetite.

At least 35 states have had cases, and they seem to crop up a few weeks after local COVID-19 activity peaks, said Dr. Adrienne Randolph of Boston Children's Hospital. The second paper involved 99 children in NY state, where the first US cases occurred.

Combined, the papers show 285 cases from March thru mid to late May but Randolph said additional USA children have been diagnosed in June.

"While they are confirmed from our current definition, that definition does not now require a diagnosis of COVID-19 because we want to make sure we don't miss any cases in this early information-gathering phase".

In both studies, numerous children developed cardiovascular problems and gastrointestinal problems. "But I guess it kind of highlights the need to take sensible precautions where you can", said Dr. Lynora Saxinger, an infectious disease specialist at the University of Alberta. "This is a life-threatening concern for a lot of patients".

In fact, one of the only common denominators they found was that in about 30% of cases, the children were obese.

Randolph said the average age of the children affected was about 8 years old.

Other reports by Click Lancashire

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