Study Shows BPA-Free Plastic Comes With Reproductive Issues in Mice Trials

Henrietta Strickland
September 17, 2018

We look for labels stating plastics are "BPA-free" to reassure ourselves that the product is safe to eat or drink out of.

And her advice to consumers now is simple: BPA-free or not, "plastic products that show physical signs of damage or ageing can not be considered safe". Bisphenol A is a chemical widely used to create plastic. The chemical has been used since the 1960's according to the US Food and Drugs Administration (US FDA).

BPA has always been used in plastic products such as soda pop and reusable water bottles, as well as food-can coatings. When exposed to heat (for example from the microwave) or if the container is damaged, this chemical gets mixed with the food and can be ingested.

Although determining the levels of human exposure is hard, the controlled experiments were conducted using low doses of BPS and other replacement bisphenols thought to be relevant to exposure in people using BPA-free plastics.

Now, the same team identified reproductive problems in some of the male and female mice that they were using for another project. After 15 years of research doctors have proven the danger of this substance and banned it, replacing it with more harmless BSP. The long term effects of BPA exposure are however not fully understood in humans.

There have been previous studies confirming that danger still prevails in BPA-free plastic, but this latest one may make consumers think twice about plastic products in general, BPA-free or not. The mice were not clear of the effects until about the fourth or fifth generation. The researchers believe that this could hold true for humans as well.

But in recent studies, Hunt and her colleagues again noticed odd results in their mice, as reported in Current Biology. This capacity that, amid fears it might perchance perchance ranking an heed on fertility amongst assorted things, its spend has in most cases been ceased in merchandise supposed for babies, while health-mindful adults customarily detect for BPA-free alternatives too.

This time round, it was plastic cages housing mice being feeble as care for an eye on animals in review Hunt was endeavor that flagged a skill situation.

In step with a specialize in at Washington Screech College, on the other hand, a number of the frequent BPA replacements in plastic can ranking downsides of their receive. To the surprise of the researchers, the animals that were not administered BPA (the control group) also started showing genetic changes that were seen in the BPA group.

Hunt and her team just recently discovered reproductive problems in mice kept in plastic cages made with Bisphenol S (BPS), a common replacement for BPA.

It transpired that a lab worker had accidentally cleaned the cage with a different detergent; one which contained BPA. Conducted by three US agencies, it was launched "to understand why findings from traditional toxicology studies of BPA and those of independent investigators differ". They counted the number of "MLH1 foci" in the DNA of sperm and eggs - these are alterations of that indicate abnormalities in the chromosomes. The most important find was that BPS wasn't the only replacement that came with similar results. The detrimental effects of all the alternatives remained same.

Hunt recommends discontinuing use of any plastic product that show damage.

Other reports by Click Lancashire

Discuss This Article